Warframe Omega Isotope Farm: How to Get Omega Isotopes to Craft a Fomorian Disruptor

Here are some ways to farm the Omega Isotope in Warframe.

by Elliott Gatica



The Balor Fomorian event is currently live on PC, so make sure to gear up and help your fellow Tenno in defending the Orcus Relay on Pluto. You can’t outright take on the special timed mission from the get-go. You’re going to need a specific resource after acquiring the Fomorian Disruptor blueprint from the Lotus. You’ll notice you need the Omega Isotope and need to farm quite a lot of them, so here’s how to do that in Warframe.

How to Farm Omega Isotope in Warframe

While a Balor Fomorian is active on a planet, you can obtain Omega Isotopes from all the missions on that planet. They just become another uncommon resource, similar to Orokin Cells, Neurodes, Gallium, and other resources that come in single units. Like the uncommon and rarer resources, your best bet is to take on missions with high enemy density. For example, this invasion is taking place on Pluto, so the best places to farm would be the Survival mission, Palus, or the Dark Sector Excavation mission, Hieracon.

To increase the drop chances of rare items, including the elusive Omega Isotope, use slash-based weapons. Next, you’d want to bring a Nekros equipped with a Despoil augment, a Khora with a Pilfering Strangledome mod, or a Hydroid with Pilfering Storm. Basically, by using at least one of these frames with their respective augments, you’re increasing loot drops per enemy in endless missions.


You can increase the enemy count with more players in the session, which will start to benefit all of you in endless missions. The best ones are survival and excavation since you don’t have to worry about a possible mission failure from something like defense.

Finally, if you want to increase your chances even further by using all the above methods, try going into a populated relay and hope that a Rank 30 or higher player blesses the lobby with a Resource Drop Chance Blessing. This also stacks with Resource Boosters that you can buy in the store.

Warframe is free to play right now on PlayStation 4 and 5, Xbox One and Series X/S, PC, and Nintendo Switch.

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